The Comfort Inn and Suites near the Medical Center in San Antonio, Texas, ensures you're rested and ready for business or leisure. We're near the San Antonio River Walk, South Texas Medical Center, and San Antonio International Airport. Our guests enjoy amenities including a free hot breakfast, free WiFi, a fitness center, valet cleaning service, and a business center with copy/fax services. Each comfortable guest room features a refrigerator, microwave, coffee maker, desk, flat-screen TV, hairdryer, and iron/ironing board. Select rooms offer a sofa sleeper, a hot tub, and a wet bar. Earn rewards, including free nights and gift cards, with our Choice Privileges Rewards program.