The Hampton Inn & Suites St. Louis/South I-55 is conveniently located at the I-55 and I-270 interchange, just 15 minutes from downtown St. Louis and the Gateway Arch. I-270 provides quick access to Illinois, West County, I-44, I-70, and I-64/40, as well as Lambert International Airport. Our award-winning service and beautifully appointed non-smoking guest rooms and suites offer amenities for both business and leisure travelers. Enjoy generous work surfaces, luxurious Hampton beds, 37-inch flat-panel HDTVs, and free high-speed internet access. We are within easy driving distance of many St. Louis attractions, including Six Flags, the Gateway Arch, major sports venues, museums, the zoo, and more. Explore downtown St. Louis (Busch Stadium, the Cathedral Basilica, America's Center, and more), the Fox Theater, Forest Park, Anheuser-Busch Brewery, and historic Kimmswick. Relax and unwind without leaving the hotel with our recreational amenities and comfortable accommodations.