Enjoy One of the Best Hotels in Athens, TennesseeSituated just off Interstate 75 halfway between Chattanooga and Knoxville, TN, Athens is a quiet city nestled in the foothills of the Great Smokey Mountains. Whether you're in town for business or leisure, we're sure you'll enjoy 'The Friendly City. 'Need a place to stay for your business trip? The Holiday Inn Express® Athens, TN hotel is a great choice since we're within five miles of companies like Denso Manufacturing, Johnson Controls, ThyssenKrupp and the Mayfield Dairy headquarters. You can also use our Athens, TN hotel's 24-hour business center to prepare for a presentation. Our 750-square-foot meeting room is great for hosting events, as well. If leisure activities bring you to Athens, TN, our hotel is the perfect jumping-off point to enjoy the surrounding area.